The Intestinal Obstruction Biohack includes the related maladies of Ileus and Hirschsprung disease.
Ileus may occur after abdominal or pelvic surgery. Ileus refers to the intolerance of oral intake due to inhibition of gastrointestinal propulsion without signs of mechanical obstruction. The diagnosis is often associated with surgery. Adhesions or scar tissue that form after surgery often occur.
Hirschsprung disease is an intestinal disorder characterized by the absence of nerves in parts of the intestine. Enteric nerves trigger the muscle contractions that move stool through the intestine. Without these nerves in parts of the intestine, the material cannot be pushed through, causing severe constipation or complete blockage of the intestine in people.
Intestinal obstruction is a blockage that keeps food or liquid from passing through your small intestine or large intestine (colon). Causes of intestinal obstruction may include fibrous bands of tissue (adhesions) in the abdomen that form after surgery; hernias; colon cancer; certain medications; or strictures from an inflamed intestine caused by certain conditions, such as Crohn's disease or diverticulitis.
Now, through Epigenetic Biohacking, you can take back control of your health! Science has now shown that every dis-ease known has a specific gene that isn't functioning at optimal range. It's not necessarily the blueprint passed down to you from your parents, rather, in 90% of cases, it's caused by some epigenetic factor such as pathogens, heavy metals, or toxins, for example. The good news is that, because of epigenetics, which is how your environment and lifestyle influence the expression of your genes, you can now reverse the negative expression of your genes through diet, lifestyle, and targeted supplementation thereby decreasing symptoms, and kick-starting the self-healing process.
Without intervention, the blocked parts of the intestine can die, leading to serious problems.
Symptoms
Signs and symptoms of intestinal obstruction include:
- Crampy abdominal pain that comes and goes
- Loss of appetite
- Constipation
- Vomiting
- Inability to have a bowel movement or pass gas
- Swelling of the abdomen
Causes
The most common causes of intestinal obstruction in adults are:
- Intestinal adhesions — bands of fibrous tissue in the abdominal cavity that can form after abdominal or pelvic surgery
- Hernias — portions of the intestine that protrude into another part of your body
- Colon cancer
Other possible causes of intestinal obstruction include:
- Inflammatory bowel diseases, such as Crohn's disease
- Diverticulitis — a condition in which small, bulging pouches (diverticula) in the digestive tract become inflamed or infected
- Twisting of the colon (volvulus)
- Impacted feces
Diseases and conditions that can increase your risk of intestinal obstruction include:
- Abdominal or pelvic surgery, which often causes adhesions — a common intestinal obstruction
- Crohn's disease, which can cause the intestine's walls to thicken, narrowing the passageway
- Cancer in your abdomen
Complications
Untreated, intestinal obstruction can cause serious, life-threatening complications, including:
- Tissue death. Intestinal obstruction can cut off the blood supply to part of your intestine. Lack of blood causes the intestinal wall to die. Tissue death can result in a tear (perforation) in the intestinal wall, which can lead to infection.
- Infection. Peritonitis is the medical term for an infection in the abdominal cavity. It's a life-threatening condition that requires immediate medical and often surgical attention.
This Biohack includes natural remedies for the main genes and pathways associated with Intestinal Obstruction including the recommended summary protocol for them.
Intestinal Obstruction Biohack Genes & Pathways:
- SLC26A3 Gene - Solute Carrier Family 26 Member 3 (Protein DRA)
- Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)
- MUC2 Gene - Mucin 2, Oligomeric Mucus/Gel-Forming
- Signal Transduction SuperPath
- ACTR2 Gene - Actin Related Protein 2
- CORO1A Gene - Coronin 1A
- PPP3CA Gene - Protein Phosphatase 3 Catalytic Subunit Alpha
- Cytoskeletal Signaling SuperPath
- ACTA1 Gene - Actin Alpha 1, Skeletal Muscle
- VCL Gene – Vinculin
- Rho GTPases Signaling
- Transport of inorganic cations/anions and amino acids/oligopeptides SuperPath
- RHAG Gene - Rh Associated Glycoprotein
- ANK1 Gene - Ankyrin 1
- Disorders of transmembrane transporters SuperPath
- SLC17A5 Gene - Solute Carrier Family 17 Member 5
- PYGM Gene - Glycogen Phosphorylase, Muscle Associated
- GUCY2C Gene - Guanylate Cyclase 2C
- SLC22A4 Gene - Solute Carrier Family 22 Member 4
- NOX3 Gene - NADPH Oxidase 3
- TGF-Beta Signaling
- Digestion and absorption SuperPath
- LIPF Gene - Lipase F, Gastric Type
- AMY2B Gene - Amylase Alpha 2B
- ALPI Gene - Alkaline Phosphatase, Intestinal
- LCT Gene – Lactase
- TREH Gene – Trehalase
- SLC2A2 Gene - Solute Carrier Family 2 Member 2
- MGAM Gene - Maltase-Glucoamylase
- SI Gene - Sucrase-Isomaltase
- CLPS Gene – Colipase
- Disease SuperPath
- TAB1 Gene - TGF-Beta Activated Kinase 1 (MAP3K7) Binding Protein 1
- XIAP Gene - X-Linked Inhibitor Of Apoptosis
- P38GAMMA (MAPK12 Gene - Mitogen-Activated Protein Kinase 12)
- RAF/MAP Kinase Cascade SuperPath
- ERBB4 Gene - Erb-B2 Receptor Tyrosine Kinase 4
- RET Gene - Ret Proto-Oncogene
- GDNF (glial cell-line derived neurotrophic factor)
- NRTN Gene - Neurturin
- Mitogen-Activated Protein Kinase 1 (MAPK1)
- NFKB1 Gene - Nuclear Factor Kappa B Subunit 1
- TNF Gene - Tumor Necrosis Factor
- IL6 Gene - Interleukin 6
- IL1B Gene - Interleukin 1 Beta
- IL10 Gene - Interleukin 10 (Anti-inflammatory Cytokine)
- THPO Gene – Thrombopoietin
- Vasoactive Intestinal Peptide (VIP)